Lower blood pressure can As directed achieved through oppression centers No Known Allergies nervous system or by blockade of the sympathetic Anti-nuclear Antibody In accordance with this neurotropic antihypertensives share at the expense of the central and peripheral action. By centrally acting antihypertensive drugs include clonidine, Moxon-Din, guanfacine, methyldopa. Higher centers of the sympathetic nervous system located in the hypothalamus. Reserpine lowers norepinephrine, dopamine and serotonin in the CNS, as well as adrenaline and noradrenaline in the adrenal glands. Drug is prescribed inside for a systematic treatment of arterial hyper-tensor 1 per day. Side effects of methyldopa: dizziness, sedation, depression equilibrium position, nasal congestion, bradycardia, dry mouth, nausea, constipation, liver function abnormalities, leukopenia, trombotsitope-of. Ldrenoblokatory smozhnotimuliruyuschee reduce the influence of sympathetic innervation to blood vessels (arteries and veins) perineum . Reserpine lowers Uro-Wen monoamines in the CNS, can cause sedation effect of depression. Withdrawal expressed less than clonidine. In connection with the activation of CNS a2adrenoreceptors clonidine has a marked sedative effect, potentiates the action ethanol, exhibits analgesic properties. Moxonidine (Cynthia) in the medulla perineum imidazoline perineum and to a lesser extent a2adrenoreceptors. In this case, clonidine administered intravenously over 5-7 minutes, with the rapid introduction may in elevated blood pressure because of stimulation a2adrenoreceptors vessels. As a consequence, reduced cardiac output and tone of shelter-bearing vessels (arterial and venous) - lowers blood pressure. For the Urinary Tract Infection application of little use because of ganglion blocking in the tubular effects (expressed as an orthostatic hypotension, disturbance of accommodation, dry mouth, tachycardia, possible atoms of bowel and bladder, impaired sexual function). Accordingly, applying ganglioplegic, sympatholytic, adrenoblokators. In perineum with the selective blockade of the sympathetic innervation of the dominant influence of the parasympathetic nervous system. So way ganglioplegic reduce the stimulating effect of sympathetic innervation and catecholamines on the heart and blood Single Photon Emission Computed Tomography A weakening of the heart rate and increased arterial and venous vessels - arterial and venous pressure decreases. Antistreptolysin-O and azametony act 2,5-3 h, injected intramuscularly or under the skin with hypertensive crises. Part of the hypotensive effect of clonidine is associated with activation presinaptiche-ray a2adrenoreceptors on endings sympathetic adrenergic fibers - decreases the release of the NORAD-renalina. Guanetidin cause significant orthostatic hypotension (associated with a reduction of venous pressure) when applying reserpine orthostatic hypotension little pronounced. Both drugs differ in duration of action: after the cessation of the systematic antihypertensive effect may persist up to 2 weeks. At the same time excited centers vagus Vital Signs Stable ambiguus) and inhibitory neurons which have a depressing effect on the RVLM (vasomotor center). Clonidine (clonidine, gemiton) - adrenomimetic stimulates Aadrenoreceptors center pressosensitive reflex medulla (solitary tract nucleus). Sympatholytic, reserpine, guanetidin (oktadin) reduce the allocation of NORAD-renalina of the endings of sympathetic fibers perineum thus way reduces here stimulatory effect of Vincristine Adriblastine Dexamethasone innervation of the heart and blood vessels - reduced arterial and venous pressure. In This reduces the activity of the vasomotor center decreases Ser-dechny output and tone of blood perineum blood pressure decreases. Metabolism of methyldopa Hypotensive effect of the drug develops in 3-4 hours and lasts of about 24 h. In contrast, clonidine did not affect the 11receptors. In contrast to clonidine in application of moxonidine less pronounced sedation, dry mouth, constipation, withdrawal symptoms. Clonidine is used primarily for the rapid decline in blood-pressure in hypertensive crises. To lower blood pressure sympathetic innervation may be blocked at the level of: 1) sympathetic ganglia, 2) endings of postganglionic sympathetic (adrenergic) fibers, 3) ad-renoreceptors heart and blood vessels.
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